Imatinib is used to treat chronic myeloid leukemia , gastrointestinal stromal tumors , and other diseases. In chronic myeloid leukemia, ABL, a tyrosine kinase , is always activated. Imatinib attaches to the active site of tyrosine kinase and blocks its activity. Imatinib is the first new substan...
Imatinib is known under the brand name Gleevec. Imatinib is used to treat adults who have newly developed certain types of acute lymphoblastic leukemia (Ph1 ALL) and Ph1 (rebellious) ALL that have not responded to the action of other medications. Imatinib is also used to treat Darier-Ferrand derm...